Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624298 | 1.00 | LMNA (0.67) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| SCHEMBL23903383 | 1.00 | LMNA (0.67) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| SCHEMBL29001187 | 0.99 | LMNA (0.65) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL4271423 | 0.99 | LMNA (0.65) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| SCHEMBL23926881 | 0.99 | LMNA (0.64) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| SCHEMBL27623813 | 0.93 | ALDH1A1 (0.56) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| SCHEMBL5987475 | 0.93 | LMNA (0.58) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| SCHEMBL8213632 | 0.91 | FAAH (0.57) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| SCHEMBL23069546 | 0.88 | L3MBTL1 (0.60) | LMNAL3MBTL1MAPTNFKB1NFKB2 | |
| SCHEMBL27094819 | 0.86 | CYP3A4 (0.50) | LMNAL3MBTL1MAPTNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120917-B1 | Method for alleviating side effects of retinoic acid therapy and/or improving efficacy without interfering with efficacy | UNIV KENTUCKY RES FOUND (US) | 2014-01-22 | — | — | EP | claimed |
| US-20100173957-A1 | METHOD FOR ALLEVIATING SIDE EFFECTS OF RETINOIC ACID THERAPY AND/OR IMPROVING EFFICACY WITHOUT INTERFERING WITH EFFICACY | NIADYNE, INC. | 2010-07-08 | — | — | US | claimed |
| JP-2010520202-A | — | — | 2010-06-10 | — | — | JP | claimed |
| EP-2120917-A2 | METHOD FOR ALLEVIATING SIDE EFFECTS OF RETINOIC ACID THERAPY AND/OR IMPROVING EFFICACY WITHOUT INTERFERING WITH EFFICACY | University Of Kentucky Research Foundation (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2008106177-A2 | METHOD FOR ALLEVIATING SIDE EFFECTS OF RETINOIC ACID THERAPY AND/OR IMPROVING EFFICACY WITHOUT INTERFERING WITH EFFICACY | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-09-04 | — | — | WO | claimed |
| CN-120000544-A | Use of compounds and compositions thereof for reducing muscle tone | 上海克琴科技有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-115400140-B | Use of ribofuranosylpyridine derivatives for the prevention or treatment of epilepsy or convulsions | 宁波熙健医药科技有限公司 | 2024-02-20 | — | — | CN | disclosed |