Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22835020 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4830079 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL17163937 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25177394 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL22835017 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25184994 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25199003 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25211905 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL20820026 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL1147991 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459479-A | Dumbbell-type fullerene condensed ring derivative and preparation method and application thereof | 中国科学院化学研究所 | 2024-08-09 | — | — | CN | claimed |
| EP-3169403-B9 | ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES | PROTAGONIST THERAPEUTICS INC (US) | 2024-07-03 | — | — | EP | claimed |
| EP-3169403-B1 | ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES | PROTAGONIST THERAPEUTICS INC (US) | 2024-02-14 | — | — | EP | claimed |
| WO-2024030977-A2 | NOVEL MELANOCORTIN ANALOGS | SIGHTSTREAM BIOTHERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | claimed |
| CN-116840387-A | Potential typing metabolic marker for nephrotic syndrome and metabolic marker related to lesion process and application of potential typing metabolic marker | 山西大学 | 2023-10-03 | — | — | CN | claimed |
| CN-114507303-A | External electron donor for olefin polymerization, catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-114478870-A | Catalyst system for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-107206254-B | Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel disease | 领导医疗有限公司 | 2021-08-24 | — | — | CN | claimed |
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2018-07-10 | — | — | US | claimed |
| EP-2836485-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2018-01-10 | — | — | EP | claimed |
| WO-2005066207-A1 | GLUCAGON-LIKE PEPTIDE-1 ANALOGS WITH LONG DURATION OF ACTION | THERATECHNOLOGIES INC. (CA) | 2005-07-21 | — | — | WO | claimed |
| US-6864229-B2 | G protein coupled receptor (GPCR) agonists and antagonists and methods of activating and inhibiting GPCR using the same | NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. (US) | 2005-03-08 | — | — | US | claimed |
| US-20030148449-A1 | G protein coupled receptor agonists and antagonists and methods of activating and inhibiting G protein coupled receptors using the same | TUFTS MEDICAL CENTER, INC. | 2003-08-07 | — | — | US | claimed |
| EP-1278777-A2 | G PROTEIN COUPLED RECEPTOR (GPCR) AGONISTS AND ANTAGONISTS AND METHODS OF ACTIVATING AND INHIBITING GPCR USING THE SAME | New England Medical Center (US) | 2003-01-29 | — | — | EP | claimed |
| WO-2001081408-A9 | G-PROTEIN COUPLED RECEPTOR (GPCR) AGONISTS AND ANTAGONISTS AND METHODS OF ACTIVATING AND INHIBITING GPCR USING THE SAME | NEW ENGLAND MEDICAL CT (US) | 2003-01-03 | — | — | WO | claimed |
| US-20020076755-A1 | G protein coupled receptor (GPCR) agonists and antagonists and methods of activating and inhibiting GPCR using the same | TUFTS MEDICAL CENTER, INC. | 2002-06-20 | — | — | US | claimed |
| JP-2002507591-A | — | — | 2002-03-12 | — | — | JP | claimed |
| WO-2001081408-A2 | G-PROTEIN COUPLED RECEPTOR (GPCR) AGONISTS AND ANTAGONISTS AND METHODS OF ACTIVATING AND INHIBITING GPCR USING THE SAME | NEW ENGLAND MEDICAL CENTER (US) | 2001-11-01 | — | — | WO | claimed |
| EP-1064254-A2 | ALIPHATIC AMINO CARBOXYLIC AND AMINO PHOSPHONIC ACIDS, AMINO NITRILES AND AMINO TETRAZOLES AS CELLULAR RESCUE AGENTS | University of Saskatchewan Technologies Inc. (CA) | 2001-01-03 | — | — | EP | claimed |
| WO-1999048858-A2 | ALIPHATIC AMINO CARBOXYLIC AND AMINO PHOSPHONIC ACIDS, AMINO NITRILES AND AMINO TETRAZOLES AS CELLULAR RESCUE AGENTS | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) | 1999-09-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | CTSE, CTSB, CTSS | GPR84 596/4885PPARG 1974/4885PPARD 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.