Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834341 | 1.00 | USP30 (0.53) | USP30PRMT5JAK2JAK1PDE10A | |
| SCHEMBL23360071 | 0.94 | GPR119 (0.48) | USP30PDE10AGPR119MEN1KMT2A | |
| SCHEMBL29863135 | 0.94 | GPR119 (0.48) | USP30PDE10AGPR119MEN1KMT2A | |
| SCHEMBL23360433 | 0.84 | NCF1 (0.43) | USP30JAK2JAK1PDE10A | |
| SCHEMBL23360434 | 0.84 | NCF1 (0.43) | USP30JAK2JAK1PDE10A | |
| SCHEMBL28834127 | 0.81 | USP30 (0.52) | USP30PRMT5JAK2JAK1GPR119 | |
| SCHEMBL29862516 | 0.81 | USP30 (0.52) | USP30PRMT5JAK2JAK1GPR119 | |
| SCHEMBL29862723 | 0.81 | USP30 (0.52) | USP30PRMT5JAK2JAK1GPR119 | |
| SCHEMBL28834124 | 0.81 | USP30 (0.52) | USP30PRMT5JAK2JAK1GPR119 | |
| SCHEMBL28834159 | 0.81 | USP30 (0.52) | USP30PRMT5JAK2JAK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055014-B1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORP (KR) | 2025-04-30 | — | — | EP | disclosed |
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | USP30 1231/4885PRMT5 206/4885JAK2 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.