Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624261 | 0.81 | SIRT6 (0.53) | MAPTALDH1A1SIRT6PDGFRBFGFR1 | |
| SCHEMBL15482828 | 0.79 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28834807 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1SIRT6PDGFRBFGFR1 | |
| SCHEMBL29901692 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1SIRT6PDGFRBFGFR1 | |
| Acetic Acid SCHEMBL10988192 | 0.77 | ALDH1A1 (0.51) | MAPTALDH1A1SIRT6TDP1MEN1 | |
| SCHEMBL21468508 | 0.77 | SIRT6 (0.50) | MAPTALDH1A1SIRT6PDGFRBFGFR1 | |
| SCHEMBL2205220 | 0.77 | ALDH1A1 (0.57) | MAPTALDH1A1SIRT6TDP1MEN1 | |
| SCHEMBL29581365 | 0.77 | ALDH1A1 (0.57) | MAPTALDH1A1SIRT6TDP1MEN1 | |
| SCHEMBL14539708 | 0.76 | MAPT (0.41) | MAPTALDH1A1PDGFRBFGFR1PDGFRA | |
| SCHEMBL8526291 | 0.74 | HTR2A (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |