Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29267729 | 0.83 | SIRT6 (0.47) | SIRT6GAARXFP1ALDH1A1MAPT | |
| SCHEMBL28834853 | 0.83 | DGAT1 (0.41) | DGAT1GAAALDH1A1MAPTKDM4E | |
| SCHEMBL30184037 | 0.73 | KDM4E (0.47) | SIRT6ALDH1A1MAPTTDP1MAPK1 | |
| SCHEMBL23578505 | 0.73 | KDM4E (0.47) | SIRT6ALDH1A1MAPTTDP1MAPK1 | |
| SCHEMBL2916543 | 0.72 | MAPT (0.54) | SIRT6GAARXFP1ALDH1A1MAPT | |
| SCHEMBL30514048 | 0.69 | MAPT (0.45) | GAARXFP1ALDH1A1MAPTLMNA | |
| SCHEMBL25389703 | 0.69 | MAPT (0.45) | GAARXFP1ALDH1A1MAPTLMNA | |
| SCHEMBL5624516 | 0.69 | SIRT6 (0.58) | SIRT6RXFP1ALDH1A1MAPTTDP1 | |
| SCHEMBL28834792 | 0.68 | SIRT6 (0.42) | SIRT6GAAALDH1A1MAPTTDP1 | |
| SCHEMBL4677098 | 0.67 | TDP1 (0.49) | SIRT6ALDH1A1MAPTTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |