Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834826 | 0.83 | SIRT6 (0.45) | DGAT1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL21231982 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL28834873 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL30184190 | 0.70 | BRPF1 (0.49) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL23577596 | 0.70 | BRPF1 (0.49) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL2924795 | 0.69 | S100B (0.56) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL30326002 | 0.69 | S100B (0.56) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL20595044 | 0.67 | KDM1A (0.51) | DGAT1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL25387340 | 0.67 | BRPF1 (0.53) | KDM4EALDH1A1HSD17B10BRD4RAB9A | |
| SCHEMBL22140394 | 0.66 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |