Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834819 | 0.83 | ALDH1A1 (0.44) | MAPTGAAHPGDLMNAALDH1A1 | |
| SCHEMBL29901699 | 0.80 | SIRT6 (0.41) | SIRT6MAPTSMN1; SMN2HPGDHTT | |
| SCHEMBL28834777 | 0.79 | CNR2 (0.40) | SIRT6SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL20606477 | 0.75 | IRAK4 (0.55) | SIRT6 | |
| SCHEMBL3359093 | 0.73 | ALDH1A1 (0.41) | KMT2AMEN1MAPTGAASMN1; SMN2 | |
| SCHEMBL31438003 | 0.72 | FGFR1 (0.43) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL15998985 | 0.72 | HTR3A (0.43) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20606373 | 0.72 | IRAK4 (0.49) | SIRT6 | |
| SCHEMBL20606510 | 0.72 | IRAK4 (0.49) | SIRT6 | |
| SCHEMBL29267729 | 0.71 | SIRT6 (0.47) | SIRT6KMT2AMEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |