SCHEMBL28835484

SCHEMBL28835484

c1ccc(C2=C(c3ccccc3)C(c3ccccc3)CCCC2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.38
ALOX15 P16050 1/20 0.38
NOS1 P29475 2/20 0.38
NOS2 P35228 2/20 0.38
HRH4 Q9H3N8 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
CFTR P13569 1/20 0.35
GOPC Q9HD26 1/20 0.35
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
FGF23 Q9GZV9 1/20 0.34
PTGS2 P35354 1/20 0.34
TP53 P04637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SLC18A3 Q16572 2/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28512805 0.98 IGF1R (0.37) IGF1RALOX15NOS1NOS2HRH4
SCHEMBL14653402 0.76 IGF1R (0.50) IGF1RALOX15DDB1CRBNCFTR
SCHEMBL170541 0.76 IGF1R (0.41) IGF1RALOX15NOS1NOS2HRH4
SCHEMBL28220437 0.75 CFTR (0.44) CFTRGOPCALDH1A1GAASLC18A3
SCHEMBL31059233 0.72 FGF23 (0.37) HRH3CFTRGOPCFGF23PTGS2
SCHEMBL28039210 0.71 IGF1R (0.39) IGF1RALOX15DDB1CRBNCFTR
SCHEMBL8653245 0.71 PTGS2 (0.54) CFTRGOPCALDH1A1FGF23PTGS2
SCHEMBL31059234 0.70 FGF23 (0.40) CFTRGOPCALDH1A1FGF23PTGS2
SCHEMBL31059231 0.70 FGF23 (0.40) CFTRGOPCALDH1A1FGF23PTGS2
SCHEMBL4054268 0.70 DDB1 (0.41) IGF1RALOX15NOS1NOS2DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107353890-B Polycyclic compound and organic electroluminescent device including the same 三星显示有限公司 2022-09-02 CN disclosed