SCHEMBL8653245

SCHEMBL8653245

c1ccc(C2=C(c3ccccc3)CCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.54
FGF23 Q9GZV9 1/20 0.48
CFTR P13569 1/20 0.48
GOPC Q9HD26 1/20 0.48
ALDH1A1 P00352 1/20 0.47
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
TSHR P16473 1/20 0.45
KMT2A Q03164 1/20 0.41
HPGD P15428 1/20 0.39
MAPK14 Q16539 1/20 0.38
NPC1 O15118 2/20 0.37
MAPK1 P28482 2/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GLA P06280 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8705170 0.97 PTGS2 (0.52) PTGS2FGF23CFTRGOPCALDH1A1
SCHEMBL30144760 0.97 PTGS2 (0.52) PTGS2FGF23CFTRGOPCALDH1A1
SCHEMBL30877921 0.97 PTGS2 (0.52) PTGS2FGF23CFTRGOPCALDH1A1
SCHEMBL8705175 0.97 PTGS2 (0.52) PTGS2FGF23CFTRGOPCALDH1A1
SCHEMBL8518215 0.94 PTGS2 (0.59) PTGS2FGF23CFTRGOPCALDH1A1
SCHEMBL7212942 0.87 ALDH1A1 (0.53) PTGS2FGF23CFTRGOPCALDH1A1
SCHEMBL27874435 0.86 KMT2A (0.46) PTGS2FGF23CFTRGOPCALDH1A1
SCHEMBL5606620 0.85 PTGS2 (0.53) PTGS2FGF23ALDH1A1SLC6A2SLC6A4
SCHEMBL11823911 0.82 PTGS2 (0.46) PTGS2FGF23CFTRGOPCALDH1A1
SCHEMBL3243441 0.82 FGF23 (0.46) PTGS2FGF23CFTRGOPCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5229979-A None JP disclosed
US-20240114774-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-04-04 US disclosed
CN-117623944-A Amine compound, light-emitting element comprising amine compound, and display device comprising light-emitting element 三星显示有限公司 2024-03-01 CN disclosed
EP-0724566-B1 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION SEARLE & CO (US) 1998-10-07 EP disclosed
US-5663180-A ANTIARTHRITIC, ANTIINFLAMMATORY AGENTS G.D. SEARLE & CO. (US) 1997-09-02 US disclosed
EP-0724566-A1 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-08-07 EP disclosed
US-5420287-A 1,2 diarylcyclopentenyl compounds for the treatment of inflammation G. D. SEARLE & CO. (US) 1995-05-30 US disclosed
WO-1995011883-A1 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-05-04 WO disclosed
US-5344991-A Sulfonyl or sulfamyl derivatives for treatment of arthritis and pain G.D. SEARLE & CO. (US) 1994-09-06 US disclosed
JP-H05229979-A NEW BIPHENYLCYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION KANTO CHEM CO INC 1993-09-07 JP disclosed
US-4401537-A EPOXIDE, ONIUM CATALYST AND 3-GLYCIDOXYPROPYL/TRIETHOXYSILANE; CHEMICAL RESISTANCE; ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240114774-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME CRY1, SLC1A2, CRY2 PTGS2 3509/4885FGF23 1213/4885CFTR 4836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.