Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31059234 | 1.00 | FGF23 (0.40) | FGF23BRD3ACHECYP1A2CYP2C9 | |
| SCHEMBL24807917 | 0.79 | SLC6A3 (0.41) | FGF23BRD3ACHECYP1A2CYP2C9 | |
| SCHEMBL30636598 | 0.79 | FGF23 (0.39) | FGF23BRD3ACHECYP1A2CYP2C9 | |
| SCHEMBL31059233 | 0.78 | FGF23 (0.37) | FGF23PTGS2SLC6A3LMNACFTR | |
| SCHEMBL6810992 | 0.77 | DHODH (0.43) | BRD3ACHECYP1A2CYP2C9TSHR | |
| SCHEMBL7486945 | 0.73 | PTGS2 (0.59) | ALDH1A1PTGS2 | |
| SCHEMBL8192883 | 0.71 | PSIP1 (0.45) | PTGS2 | |
| SCHEMBL30144692 | 0.71 | SLC6A2 (0.42) | FGF23TSHRALDH1A1PTGS2SLC6A3 | |
| SCHEMBL30144695 | 0.71 | SLC6A2 (0.42) | FGF23TSHRALDH1A1PTGS2SLC6A3 | |
| SCHEMBL28835484 | 0.70 | IGF1R (0.38) | FGF23ALDH1A1PTGS2SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504706-A | Macrocyclic compounds having farnesyl transferase inhibitory activity | 库拉肿瘤学公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-118339152-A | Macrocyclic compounds having farnesyl transferase inhibitory activity | 库拉肿瘤学公司 | 2024-07-12 | — | — | CN | disclosed |