Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186457 | 0.86 | CES2 (0.50) | LMNACES2CES1ESR1ESR2 | |
| SCHEMBL27884621 | 0.85 | LMNA (0.56) | LMNACES2CES1ESR1ESR2 | |
| SCHEMBL28097763 | 0.84 | PARP1 (0.54) | LMNACES2CES1ESR1ESR2 | |
| SCHEMBL28765751 | 0.84 | LMNA (0.54) | LMNACES2CES1ESR1ESR2 | |
| SCHEMBL4453562 | 0.81 | CES2 (0.53) | LMNACES2CES1ESR1ESR2 | |
| SCHEMBL28855688 | 0.81 | LMNA (0.49) | LMNACES2CES1ESR1ESR2 | |
| SCHEMBL9671485 | 0.81 | LMNA (0.59) | LMNACES2CES1ESR1ESR2 | |
| SCHEMBL10787286 | 0.80 | CYP3A4 (0.59) | LMNAESR1ESR2POLBPARP1 | |
| SCHEMBL17352101 | 0.79 | MTNR1B (0.50) | LMNACES2CES1 | |
| SCHEMBL27699824 | 0.79 | MMP1 (0.54) | KDM4ENPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105998040-A | Preparation method of medicine for treating cardiovascular disease | 胡小丽 | 2016-10-12 | — | — | CN | claimed |