Isonicotinic Acid

Isonicotinic Acid

SCHEMBL28836313

CC1(C)CCCC(C)(C)N1.O=C(O)c1ccncc1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.57
GAA P10253 3/20 0.41
RECQL P46063 1/20 0.41
CYP2C9 P11712 5/20 0.40
CYP2D6 P10635 3/20 0.40
TSHR P16473 2/20 0.40
USP2 O75604 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP3A4 P08684 6/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP2C19 P33261 4/20 0.38
LMNA P02545 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.37
NPC1 O15118 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL6544696 0.88 TP53 (0.48) TSHRCYP3A4ALDH1A1
Benzoic Acid SCHEMBL23581094 0.84 TSHR (0.52) NAPRTGAACYP2C9CYP2D6TSHR
Isophthalic Acid SCHEMBL6544630 0.78 CA12 (0.44) GAACYP2C9HSD17B10MEN1KMT2A
Isonicotinic Acid SCHEMBL1108 0.75
Isonicotinic Acid SCHEMBL1414914 0.75 NAPRT (1.00) NAPRTGAACYP2C9CYP2D6TSHR
Ammonia Solution, Strong SCHEMBL28860839 0.74 RXRA (0.42) GAARECQLUSP2MEN1KMT2A
Phthalic Acid SCHEMBL8067893 0.74 ALOX15 (0.52) NAPRTGAACYP2C9CYP2D6CYP3A4
Phthalic Acid SCHEMBL6544237 0.74 ALOX15 (0.52) NAPRTGAACYP2C9CYP2D6CYP3A4
Isonicotinic Acid SCHEMBL6877555 0.73 NAPRT (0.85) NAPRTGAACYP2C9CYP2D6TSHR
Isonicotinic Acid SCHEMBL25222705 0.73 NAPRT (0.94) NAPRTGAACYP2C9CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115023426-A Pesticidally active heterocyclic derivatives with sulfur-containing substituents 先正达农作物保护股份公司 2022-09-06 CN disclosed