Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564357 | 0.84 | ICMT (0.47) | MEN1KMT2ACDK2KDM4EMAPT | |
| SCHEMBL2085331 | 0.84 | KDM4E (0.51) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL30275134 | 0.84 | MEN1 (0.50) | MEN1KMT2AIDO1TDO2CDK2 | |
| SCHEMBL5447791 | 0.83 | KDM4E (0.44) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL31498840 | 0.80 | KDM4E (0.65) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL4012453 | 0.80 | KDM4E (0.65) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL18508627 | 0.79 | DRD2 (0.50) | MEN1KMT2AIDO1TDO2CDK2 | |
| SCHEMBL7524516 | 0.78 | MAPT (0.44) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL2081872 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL30275080 | 0.77 | LMNA (0.48) | MEN1KMT2AIDO1TDO2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292557-B | Pyridopyrimidinone mesoion derivative containing indole unit and preparation method and application thereof | 贵州大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-113292557-A | Pyridopyrimidinone mesoion derivative containing indole unit and preparation method and application thereof | 贵州大学 | 2021-08-24 | — | — | CN | disclosed |