Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | CD4 | P01730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836713 | 0.91 | MEN1 (0.38) | HSD17B10KCNN4KCNA3MEN1KMT2A | |
| SCHEMBL30688098 | 0.85 | KCNN4 (0.56) | KCNN4KCNA3CTSGCMA1HSD11B1 | |
| SCHEMBL29101134 | 0.85 | KCNN4 (0.56) | KCNN4KCNA3CTSGCMA1HSD11B1 | |
| SCHEMBL28952599 | 0.82 | HSD17B10 (0.43) | HSD17B10KCNN4KCNA3MEN1KMT2A | |
| SCHEMBL29714451 | 0.81 | KCNN4 (0.54) | KCNN4KCNA3CTSGCMA1L3MBTL1 | |
| SCHEMBL28836746 | 0.81 | KCNN4 (0.54) | KCNN4KCNA3CTSGCMA1L3MBTL1 | |
| SCHEMBL30688097 | 0.80 | LMNA (0.52) | KCNN4KCNA3MEN1KMT2AHSD11B1 | |
| SCHEMBL29101145 | 0.80 | LMNA (0.52) | KCNN4KCNA3MEN1KMT2AHSD11B1 | |
| SCHEMBL28836744 | 0.77 | TSHR (0.48) | KCNN4KCNA3MEN1KMT2ACTSG | |
| SCHEMBL28836780 | 0.77 | KCNN4 (0.50) | KCNN4KCNA3MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716374-A | 3-substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2022-07-08 | — | — | CN | disclosed |