Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.60 |
| ▸ | STS | P08842 | 3/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 11/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DAB2IP | Q5VWQ8 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14252890 | 0.87 | STS (0.68) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL4825753 | 0.87 | STS (0.68) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL5143409 | 0.84 | SHBG (0.74) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL4826003 | 0.84 | SHBG (0.61) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL4083803 | 0.81 | SHBG (0.70) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL10054959 | 0.81 | SHBG (0.70) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL4075005 | 0.80 | HSD17B1 (0.69) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL10439769 | 0.80 | HSD17B1 (0.70) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL4082465 | 0.80 | SHBG (0.68) | SHBGSTSHSD17B1ESR1CYP19A1 | |
| SCHEMBL3972911 | 0.79 | CYP19A1 (0.69) | SHBGSTSHSD17B1ESR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114040986-A | Method of diagnosing disease | 4D制药科克有限公司 | 2022-02-11 | — | — | CN | disclosed |