Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.61 |
| ▸ | STS | P08842 | 2/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DAB2IP | Q5VWQ8 | 1/20 | 0.47 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825753 | 0.88 | STS (0.68) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL14252890 | 0.88 | STS (0.68) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL5143409 | 0.85 | SHBG (0.74) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL28836993 | 0.84 | SHBG (0.60) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL4075005 | 0.83 | HSD17B1 (0.69) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL14252901 | 0.82 | HSD17B1 (0.73) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL4822516 | 0.82 | ESR1 (0.73) | SHBGESR1ESR2KDM4EMEN1 | |
| SCHEMBL4822462 | 0.82 | HSD17B1 (0.73) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL4822522 | 0.82 | ESR1 (0.73) | SHBGESR1ESR2KDM4EMEN1 | |
| SCHEMBL14252896 | 0.82 | ESR1 (0.73) | SHBGESR1ESR2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342004-B2 | Thioether sulphamate steroids as steroid inhibitors and anti-cancer compounds | STERIX LTD. (GB) | 2008-03-11 | — | — | US | disclosed |
| US-20040009959-A1 | Thioether sulphamate steroids as steroid inhibtors and anti-cancer compounds | STERIX LIMITED (GB) | 2004-01-15 | — | — | US | disclosed |
| EP-1311534-A1 | THIOETHER-SULPHAMATE STEROIDS AS STEROID SULPHATASE INHIBITORS AND ANTI-CANCER COMPOUNDS | Sterix Limited (GB) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002015910-A1 | 2-SUBSTITUTED ESTRADIOL DERIVATIVE FOR INHIBITING SUPEROXID DISMUTASE | STERIX LIMITED (GB) | 2002-02-28 | — | — | WO | disclosed |
| WO-2002016394-A1 | THIOETHER-SULPHAMATE STEROIDS AS STEROID SULPHATASE INHIBITORS AND ANTI-CANCER COMPOUNDS | STERIX LIMITED (GB) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009959-A1 | Thioether sulphamate steroids as steroid inhibtors and anti-cancer compounds | SULT1E1, HSD17B11, CYP17A1 | SHBG 7/4885STS 12/4885HSD17B1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.