Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.49 |
| ▸ | MTOR | P42345 | 3/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837689 | 0.79 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL9718852 | 0.77 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL20715329 | 0.76 | HSD17B10 (1.00) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL2359465 | 0.74 | CYP1A2 (0.68) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL20433846 | 0.72 | GAA (0.70) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL17661777 | 0.71 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL19770312 | 0.70 | TP53 (0.54) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL20565860 | 0.70 | HDAC3 (0.70) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL20715331 | 0.69 | DRD2 (0.69) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL4917592 | 0.69 | HDAC3 (0.56) | RAB9ANPC1SMN1; SMN2TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890952-B | Preparation method of 5-halogeno-2-aminobenzoazacyclic compound | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-114890952-A | Preparation method of 5-halogenated-2-aminobenzene nitrogen heterocyclic compound | 重庆医科大学 | 2022-08-12 | — | — | CN | disclosed |