Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.59 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.59 |
| ▸ | GALR3 | O60755 | 1/20 | 0.59 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28771058 | 0.83 | ALDH1A1 (0.71) | DRD2TBXA2RMAPTALDH1A1KDM4E | |
| SCHEMBL27898218 | 0.83 | ALDH1A1 (0.76) | DRD2TBXA2RMAPTNOD1ALDH1A1 | |
| SCHEMBL27915822 | 0.83 | ALDH1A1 (0.76) | DRD2TBXA2RMAPTNOD1ALDH1A1 | |
| SCHEMBL1170123 | 0.83 | SMN1; SMN2 (0.74) | DRD2TBXA2RMAPTNOD1ALDH1A1 | |
| SCHEMBL20715451 | 0.81 | NOD2 (0.67) | DRD2TBXA2RMAPTNOD1ALDH1A1 | |
| SCHEMBL17465144 | 0.79 | P2RX3 (0.70) | DRD2TBXA2R | |
| SCHEMBL15180676 | 0.78 | P2RX3 (0.68) | — | |
| SCHEMBL8734474 | 0.77 | NOD1 (0.70) | DRD2TBXA2RNOD1ALDH1A1NOD2 | |
| SCHEMBL28490322 | 0.77 | MAPT (0.85) | DRD2TBXA2RMAPTALDH1A1KDM4E | |
| SCHEMBL4097969 | 0.77 | NOD1 (0.71) | DRD2TBXA2RMAPTNOD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200377505-A1 | BENZIMIDAZOLES AND AZA-BENZIMIDAZOLES, AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2020-12-03 | — | — | US | disclosed |
| WO-2019028308-A1 | BENZIMIDAZOLES AND AZA-BENZIMIDAZOLES, AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377505-A1 | BENZIMIDAZOLES AND AZA-BENZIMIDAZOLES, AND METHODS OF USE THEREOF | AZI2, ATP6V1B1, GLS | DRD2 2400/4885TBXA2R 362/4885MAPT 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.