Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 19/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439790 | 0.83 | SLC9A1 (0.55) | SLC9A1CYP2C9CYP2C19CYP3A4ADRA1D | |
| SCHEMBL17134229 | 0.83 | SLC9A1 (0.55) | SLC9A1CYP2C9CYP2C19CYP3A4ADRA1D | |
| SCHEMBL31188362 | 0.81 | SLC9A1 (0.50) | SLC9A1CYP2C9CYP2C19CYP3A4ADRA1D | |
| SCHEMBL18584483 | 0.81 | SLC9A1 (0.41) | SLC9A1CYP2C9CYP2C19CYP3A4ADRA1D | |
| SCHEMBL3902326 | 0.79 | RBP4 (0.60) | SLC9A1CYP2C9CYP2C19CYP3A4ADRA1D | |
| SCHEMBL27452478 | 0.76 | ALDH1A1 (0.49) | CYP3A4 | |
| SCHEMBL2074095 | 0.76 | TAS1R3 (0.49) | — | |
| SCHEMBL933174 | 0.76 | SLC9A1 (0.51) | SLC9A1CYP2C9CYP2C19CYP3A4ADRA1D | |
| SCHEMBL15927479 | 0.75 | RARG (0.52) | CYP2C9 | |
| SCHEMBL20702651 | 0.75 | NPFFR2 (0.50) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573928-A | 2-aminothiazole derivative or salt thereof | 安斯泰来制药株式会社 | 2017-04-19 | — | — | CN | disclosed |
| CN-106414438-A | 2-acylaminothiazole derivative or salt thereof | 安斯泰来制药株式会社 | 2017-02-15 | — | — | CN | disclosed |