Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011431 | 0.82 | MAPT (0.45) | GABBR2GABBR1CYP2C19L3MBTL1POLB | |
| SCHEMBL27663392 | 0.82 | MAPT (0.45) | GABBR2GABBR1CYP2C19L3MBTL1POLB | |
| SCHEMBL7486608 | 0.79 | KIF11 (0.42) | GABBR2GABBR1CYP2C19HIF1AKIF11 | |
| SCHEMBL10926391 | 0.76 | GABBR2 (0.46) | GABBR2GABBR1CYP2C19L3MBTL1POLB | |
| SCHEMBL6681008 | 0.76 | KMT2A (0.58) | GABBR2GABBR1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL1545922 | 0.75 | MMP8 (0.53) | GABBR2GABBR1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28851561 | 0.73 | GABBR2 (0.43) | GABBR2GABBR1CYP2C19L3MBTL1POLB | |
| SCHEMBL8860352 | 0.73 | GABBR2 (0.43) | GABBR2GABBR1CYP2C19L3MBTL1POLB | |
| SCHEMBL377175 | 0.73 | L3MBTL1 (0.61) | GABBR2GABBR1CYP2C19L3MBTL1POLB | |
| SCHEMBL146867 | 0.73 | L3MBTL1 (0.61) | GABBR2GABBR1CYP2C19L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901690-A | Treatment of cancer with Antibody Drug Conjugates (ADCs) that bind 191P4D12 protein | 艾更斯司股份有限公司 | 2022-08-12 | — | — | CN | disclosed |