Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838991 | 0.87 | LMNA (0.40) | LMNAMAPTXBP1MAPK1HTT | |
| SCHEMBL10180637 | 0.76 | CA2 (0.58) | LMNAMAPTXBP1MAPK1HTT | |
| SCHEMBL15602775 | 0.74 | PPARG (0.49) | — | |
| SCHEMBL8609278 | 0.72 | PPARA (0.52) | — | |
| SCHEMBL8608749 | 0.72 | PPARA (0.52) | — | |
| SCHEMBL8607638 | 0.72 | PPARA (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL7879377 | 0.69 | S1PR3 (0.46) | THRBCA2 | |
| SCHEMBL29355585 | 0.68 | FUT7 (0.48) | LMNAHTTTSHRCA2 | |
| SCHEMBL22117501 | 0.68 | FUT7 (0.48) | LMNAHTTTSHRCA2 | |
| SCHEMBL11327822 | 0.68 | CA2 (0.60) | LMNAMAPTHTTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057801-A | F-18 labeled PSMA (patterned Markov chain) targeted PET (polyethylene terephthalate) probe and preparation method thereof | 西南医科大学附属医院 | 2022-09-16 | — | — | CN | disclosed |