SCHEMBL288392

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL288160	0.75	ROCK1 (0.41)	EIF4EMKNK1MKNK2HTR2AHTR2C
	SCHEMBL16071466	0.67	SMN1; SMN2 (0.58)	MKNK1MKNK2EGFRCSF1RHPGD
	SCHEMBL21524783	0.67	TUBB4A (0.45)	EIF4EMKNK1MKNK2EGFRCSF1R
	SCHEMBL4496461	0.65	GPR119 (0.42)	EIF4EMKNK1MKNK2GPR119
	SCHEMBL4496039	0.64	HTT (0.35)	HTTHTR2AHTR2CMEN1KMT2A
	SCHEMBL1673854	0.63	PIP4K2A (0.47)	EGFRHTTTSHRMAPTRXFP1
	SCHEMBL288822	0.62	SRD5A1 (0.53)	HPGDKDM4EALDH1A1MEN1KMT2A
	SCHEMBL1366102	0.62	SMN1; SMN2 (0.55)	MKNK1MKNK2EGFRCSF1RHPGD
	SCHEMBL8645023	0.61	EGFR (0.73)	EGFRCSF1RPDGFRBKDRTUBB4A
	SCHEMBL23761414	0.61	SRD5A1 (0.45)	EIF4EMKNK1MKNK2EGFRCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.