Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28081340 | 0.76 | NCF1 (0.46) | CFTRRAB9AMGAMCYP1A2LMNA | |
| SCHEMBL305634 | 0.75 | TSHR (0.50) | RAB9ALMNATSHRALDH1A1TRPM8 | |
| SCHEMBL16483982 | 0.72 | CYP1A2 (0.52) | CFTRPDGFRBPDGFRARAB9AMGAM | |
| SCHEMBL2092724 | 0.71 | TSHR (0.40) | RAB9ALMNATSHRALDH1A1TRPM8 | |
| SCHEMBL2091943 | 0.71 | MEN1 (0.48) | TSHRKMT2AMEN1 | |
| SCHEMBL2088980 | 0.71 | PTGES (0.42) | RAB9ATSHRALDH1A1KMT2A | |
| SCHEMBL2089859 | 0.71 | RAB9A (0.54) | RAB9ALMNAPOLBTSHRALDH1A1 | |
| SCHEMBL2093397 | 0.71 | PGR (0.41) | RAB9ATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5795114 | 0.71 | MGAM (0.47) | CFTRPDGFRBPDGFRARAB9AMGAM | |
| SCHEMBL27600512 | 0.71 | PDGFRB (0.62) | CFTRPDGFRBPDGFRARAB9AMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432076-B | A kind of Ciprofloxacin C3 amide derivatives and its preparation method and application | 辽宁大学 | 2019-02-19 | — | — | CN | disclosed |
| CN-106432076-A | Ciprofloxacin C3 amide derivative, preparation method thereof and application | 辽宁大学 | 2017-02-22 | — | — | CN | disclosed |