SCHEMBL28839989

SCHEMBL28839989

CC(C(=O)Oc1ccccc1)C1COCCN1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ELANE P08246 1/20 0.38
SLC6A3 Q01959 7/20 0.37
SLC6A2 P23975 5/20 0.37
SLC6A4 P31645 3/20 0.37
DHFR P00374 1/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11505237 0.78 ELANE (0.39) ATML3MBTL1ELANESLC6A3SLC6A2
SCHEMBL2026805 0.78 SLC6A3 (0.56) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL6699923 0.76 CHRNB4 (0.40) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA
SCHEMBL4954489 0.75 CPB2 (0.31) TSHR
Hydrochloric Acid SCHEMBL15572916 0.74 ALDH1A1 (0.32) ALDH1A1
SCHEMBL6598508 0.73 ALDH1A1 (0.39) ATML3MBTL1ELANEALDH1A1TDP1
SCHEMBL27751192 0.70 ELANE (0.47) ATML3MBTL1ELANESLC6A3ALDH1A1
SCHEMBL8980223 0.69 ALDH1A1 (0.35) ATML3MBTL1SLC6A3SLC6A2SLC6A4
SCHEMBL28006801 0.68 ALDH1A1 (0.51) ATML3MBTL1ELANEALDH1A1LMNA
Hydrochloric Acid SCHEMBL6683095 0.67 EPHX1 (0.38) SLC6A3SLC6A2SLC6A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907288-A Application of nitrobenzene compounds in preparation of pseudomonas aeruginosa quorum sensing inhibitor 中国医学科学院医药生物技术研究所 2022-08-16 CN disclosed