Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 19/20 | 0.41 |
| ▸ | KDM6B | O15054 | 8/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21056702 | 0.85 | KDM4C (0.53) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL29749311 | 0.85 | KDM4C (0.53) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Isonicotinic Acid SCHEMBL28218616 | 0.71 | NAPRT (0.63) | KDM4CKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL547927 | 0.70 | KDM4C (0.55) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL19284336 | 0.70 | KDM4E (0.58) | KDM4CKDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL31584153 | 0.70 | KDM4E (0.58) | KDM4CKDM4EALDH1A1KMT2AL3MBTL1 | |
| Niacin SCHEMBL9679976 | 0.70 | ALDH1A1 (0.70) | ALDH1A1THRBKMT2ATDP1 | |
| SCHEMBL31207927 | 0.70 | KDM4C (0.44) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL26600023 | 0.70 | KDM4C (0.44) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Acrylic Acid SCHEMBL8913582 | 0.69 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907317-B | Pyrazole-vinyl-isonicotinic acid derivative and preparation method and application thereof | 郑州大学 | 2023-06-13 | — | — | CN | claimed |
| CN-114907317-A | Pyrazole-vinyl-isonicotinic acid derivative and preparation method and application thereof | 郑州大学 | 2022-08-16 | — | — | CN | claimed |
| CN-114907317-B | Pyrazole-vinyl-isonicotinic acid derivative and preparation method and application thereof | 郑州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114907317-B | Pyrazole-vinyl-isonicotinic acid derivative and preparation method and application thereof | 郑州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114907317-B | Pyrazole-vinyl-isonicotinic acid derivative and preparation method and application thereof | 郑州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114907317-A | Pyrazole-vinyl-isonicotinic acid derivative and preparation method and application thereof | 郑州大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907317-A | Pyrazole-vinyl-isonicotinic acid derivative and preparation method and application thereof | 郑州大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907317-A | Pyrazole-vinyl-isonicotinic acid derivative and preparation method and application thereof | 郑州大学 | 2022-08-16 | — | — | CN | disclosed |