Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984758 | 0.84 | KDM4E (0.34) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL25515658 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL7169853 | 0.78 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL6949233 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL30401664 | 0.75 | TAAR1 (0.37) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL27283340 | 0.75 | CALM1 (0.42) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL6222799 | 0.74 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL3676449 | 0.74 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL3229293 | 0.72 | AKR1B1 (0.42) | KDM4EALDH1A1MAPTCHEK1LIMK1 | |
| SCHEMBL3258935 | 0.71 | ALOX15 (0.34) | KDM4EALDH1A1MAPTCHEK1LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136431-B | Pyridone and pyrimidone derivatives as plasma thromboplastin antecedent a inhibitor | 小野药品工业株式会社 | 2017-03-15 | — | — | CN | disclosed |