SCHEMBL28840494

SCHEMBL28840494

CO[Si](OC)(OC)OC(C)OC(C)OC(C)OC(C)OC(C)OC(C)OC(C)OC(C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
HCAR2 Q8TDS4 1/20 0.33
KMT2A Q03164 1/20 0.31
NUDT1 P36639 1/20 0.31
THRB P10828 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28840924 0.82 LTB4R (0.32) ADRA2AADRA2BADRA2CHCAR2NUDT1
SCHEMBL28840488 0.82 LTB4R (0.32) ADRA2AADRA2BADRA2CHCAR2NUDT1
SCHEMBL10629417 0.81 ADRA2A (0.40) ADRA2AADRA2BADRA2CHCAR2KMT2A
SCHEMBL28840541 0.78 LTB4R (0.33) ADRA2AADRA2BADRA2CHCAR2NUDT1
SCHEMBL17789891 0.77 THRB (0.41) ADRA2AADRA2BADRA2CHCAR2KMT2A
SCHEMBL28840493 0.73 DHFR (0.32)
SCHEMBL198133 0.72 HCAR2 (0.45) ADRA2AADRA2BADRA2CHCAR2ALDH1A1
SCHEMBL28431726 0.71 IDO1 (0.40) ADRA2AADRA2BKMT2A
SCHEMBL6272307 0.71 HCAR2 (0.46) ADRA2AADRA2BADRA2CHCAR2KMT2A
SCHEMBL7114275 0.71 KDM4E (0.43) ADRA2AADRA2BADRA2CKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115053335-A High silicon content wet removal of planarization layers 布鲁尔科技公司 2022-09-13 CN claimed