SCHEMBL28841565

SCHEMBL28841565

COc1c(C(=O)O)ccc(C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
MAPT P10636 2/20 0.58
HSD17B10 Q99714 5/20 0.50
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 4/20 0.50
HPGD P15428 2/20 0.50
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
KMT2A Q03164 1/20 0.43
SELL P14151 1/20 0.41
SELP P16109 1/20 0.41
POLB P06746 1/20 0.41
MCL1 Q07820 1/20 0.40
HAAO P46952 1/20 0.39
MYC P01106 2/20 0.39
KLKB1 P03952 1/20 0.39
CTSB P07858 1/20 0.39
ELANE P08246 1/20 0.39
MMP9 P14780 1/20 0.39
DUSP3 P51452 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1919502 0.86 TDP1 (0.50) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL17371291 0.85 TDP1 (0.68) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL6646160 0.84 TDP1 (0.52) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL1438720 0.82 TDP1 (0.59) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL1505827 0.81 TDP1 (0.61) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL4995728 0.81 TDP1 (0.49) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL11026756 0.81 MAPT (0.73) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL23213504 0.79 TDP1 (0.47) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL10373860 0.79 TDP1 (0.47) TDP1MAPTHSD17B10ALDH1A1KDM4E
SCHEMBL22245019 0.79 TDP1 (0.56) TDP1MAPTHSD17B10ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115090520-A Avermemycin mixes agent production in advance and uses particle size sieving mechanism 河北圣雪大成制药有限责任公司 2022-09-23 CN disclosed