Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | HAAO | P46952 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31643643 | 0.86 | ALDH1A1 (0.52) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL6646160 | 0.84 | TDP1 (0.52) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL1919502 | 0.82 | TDP1 (0.50) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL1505827 | 0.81 | TDP1 (0.61) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL28902668 | 0.81 | KDM4E (0.47) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL14612801 | 0.81 | TDP1 (0.53) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL28841565 | 0.81 | TDP1 (0.58) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL27673090 | 0.80 | ALDH1A1 (0.40) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL27392561 | 0.80 | KDM4E (0.44) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL195882 | 0.79 | CYP1A2 (0.44) | TDP1ALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051968-B1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | UNIV CALIFORNIA (US) | 2020-04-29 | — | — | EP | disclosed |
| CN-107835812-A | Target mutant K RAS composition and method | 南特生物科学股份有限公司 | 2018-03-23 | — | — | CN | disclosed |
| EP-2423201-B1 | Luminescent macrocyclic lanthanide complexes | UNIV CALIFORNIA (US) | 2017-10-04 | — | — | EP | disclosed |
| US-8729258-B2 | Luminescent macrocyclic lanthanide complexes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-05-20 | — | — | US | disclosed |
| US-8729258-B2 | Luminescent macrocyclic lanthanide complexes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-05-20 | — | — | US | disclosed |
| US-20120329174-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329174-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-27 | — | — | US | disclosed |
| US-8173800-B2 | Hydroxy-isophthalamide moieties; antibodies; high stability, luminescence; kits | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173800-B2 | Hydroxy-isophthalamide moieties; antibodies; high stability, luminescence; kits | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-08 | — | — | US | disclosed |
| US-20080293155-A1 | SALICYLAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS | THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080213917-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080213917-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-04 | — | — | US | disclosed |
| US-7404912-B2 | Salicylamide-lanthanide complexes for use as luminescent markers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-07-29 | — | — | US | disclosed |
| US-20060286567-A1 | Salicylamide-lanthanide complexes for use as luminescent markers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-12-21 | — | — | US | disclosed |
| US-7018850-B2 | Salicylamide-lanthanide complexes for use as luminescent markers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-03-28 | — | — | US | disclosed |
| EP-1154991-B1 | SALICYLAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS | UNIV CALIFORNIA (US) | 2004-07-28 | — | — | EP | disclosed |
| US-20030027189-A1 | Salicylamide-lanthanide complexes for use as luminescent markers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-02-06 | — | — | US | disclosed |
| US-6406297-B1 | USED FOR DETECTING AND QUANTIFYING CHEMICAL, BIOCHEMICAL AND BIOLOGICAL SUBSTANCES AS ANALYTES IN RESEARCH AND DIAGNOSTIC MIXTURES. | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-06-18 | — | — | US | disclosed |
| EP-1154991-A1 | SALICYLAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS | The Regents of the University of California (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048991-A1 | SALICYLAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213917-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | SSB, HACD3, CLTA | TDP1 4027/4885MAPT 1513/4885ALDH1A1 4586/4885 |
| US-20120329174-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | SSB, HACD3, CLTA | TDP1 4027/4885MAPT 1513/4885ALDH1A1 4586/4885 |
| US-20060286567-A1 | Salicylamide-lanthanide complexes for use as luminescent markers | SCLY, SSB, LIG3 | TDP1 1659/4885MAPT 3987/4885ALDH1A1 869/4885 |
| US-20030027189-A1 | Salicylamide-lanthanide complexes for use as luminescent markers | SCLY, SSB, LIG3 | TDP1 1659/4885MAPT 3987/4885ALDH1A1 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.