Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080235 | 0.91 | LTA4H (0.45) | LTA4HALDH1A1ATMCYP2D6LMNA | |
| SCHEMBL28131751 | 0.83 | LTA4H (0.64) | LTA4HALDH1A1ATMSMN1; SMN2TP53 | |
| SCHEMBL9341169 | 0.83 | LTA4H (0.50) | LTA4HALDH1A1ATMCYP2D6LMNA | |
| SCHEMBL2579095 | 0.83 | ALOX5 (0.54) | LTA4HALDH1A1ATMCYP2D6LMNA | |
| SCHEMBL381565 | 0.83 | LTA4H (0.50) | LTA4HALDH1A1ATMCYP2D6LMNA | |
| SCHEMBL28872975 | 0.83 | LTA4H (0.57) | LTA4HALDH1A1ATMCYP2D6LMNA | |
| SCHEMBL2576280 | 0.81 | CALM1 (0.54) | LTA4HALDH1A1ATMSMN1; SMN2TP53 | |
| SCHEMBL28251912 | 0.81 | LTA4H (0.72) | LTA4HSMN1; SMN2TP53MAPTIDO1 | |
| SCHEMBL28748801 | 0.79 | LTA4H (0.59) | LTA4HALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL146769 | 0.79 | IDH1 (0.47) | CYP2D6SMN1; SMN2NPSR1IDH1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106604727-A | Compositions and methods to improve adoptive cell therapies | 7山利益有限责任公司 | 2017-04-26 | — | — | CN | disclosed |