SCHEMBL28842913

SCHEMBL28842913

NCCC(CC(N)=O)C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
GABRR1 P24046 2/20 0.36
CPB2 Q96IY4 1/20 0.31
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
KMT2A Q03164 1/20 0.30
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9796973 0.86 CPB2 (0.47) CA1CA2GABRR1CPB2BLM
SCHEMBL14312525 0.83 GABRR1 (0.44) GABRR1CPB2ALOX15BLMPMP22
SCHEMBL293079 0.81 CA1 (0.39) CA1CA2ALOX15BLMPMP22
SCHEMBL1230306 0.80 CA1 (0.37) CA1CA2ALOX15BLMPMP22
SCHEMBL10044832 0.80 ALOX15 (0.44) CA1CA2ALOX15BLMPMP22
SCHEMBL11154563 0.79 GABRR1 (0.35) CA1CA2GABRR1ALOX15BLM
SCHEMBL28601320 0.78 CA1 (0.37) CA1CA2ALOX15BLMPMP22
SCHEMBL7353715 0.78 CA2 (0.50) CA1CA2
SCHEMBL7353712 0.78 CA2 (0.50) CA1CA2
SCHEMBL5500834 0.78 FOLH1 (0.40) CA1CA2CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104031081-B A kind of multiamide antibacterial, preparation method and applications 苏州大学 2017-03-29 CN claimed
CN-104031081-B A kind of multiamide antibacterial, preparation method and applications 苏州大学 2017-03-29 CN disclosed