Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.80 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.80 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.80 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.80 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.80 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.80 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.80 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.80 |
| ▸ | GABRP | O00591 | 6/20 | 0.80 |
| ▸ | GABRD | O14764 | 6/20 | 0.80 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.80 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.80 |
| ▸ | GABRE | P78334 | 6/20 | 0.80 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.80 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.80 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | MAPT | P10636 | 6/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Ccm SCHEMBL30480071 | 0.89 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Beta-Ccm SCHEMBL1066725 | 0.89 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Beta-Ccm SCHEMBL28185000 | 0.87 | GABRA1 (0.97) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Beta-Ccm SCHEMBL15648382 | 0.81 | GABRA1 (0.91) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20581210 | 0.76 | CTSV (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2483277 | 0.76 | KIF11 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30522267 | 0.76 | KIF11 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3341658 | 0.74 | KDM4E (0.57) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL31286006 | 0.74 | KIF11 (0.61) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22587838 | 0.74 | KIF11 (0.61) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977515-A | β carbolines, γ carboline derivatives, preparation method and the usage | 河北科技大学 | 2017-07-25 | — | — | CN | disclosed |