Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645219 | 0.89 | CCKBR (0.67) | KDM4EMTNR1AMTNR1BKMT2ACCKBR | |
| Benzene SCHEMBL9481361 | 0.87 | CCKBR (0.69) | KDM4EMTNR1AMTNR1BKMT2ACCKBR | |
| SCHEMBL3342013 | 0.79 | UTS2R (0.50) | — | |
| SCHEMBL22616930 | 0.76 | MAOA (0.86) | KDM4EMTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL1979527 | 0.75 | CCKBR (0.72) | KDM4EKMT2ACCKBRNPC1ALDH1A1 | |
| SCHEMBL2214365 | 0.75 | CCKBR (0.64) | KDM4EKMT2ACCKBRNPC1ALDH1A1 | |
| SCHEMBL30497898 | 0.75 | CCKBR (0.64) | KDM4EKMT2ACCKBRNPC1ALDH1A1 | |
| SCHEMBL28843897 | 0.74 | GABRA1 (0.80) | KDM4ENPC1ALDH1A1LMNATP53 | |
| Carbazole SCHEMBL28283104 | 0.73 | KMT2A (0.73) | KDM4EMTNR1AMTNR1BKMT2AMAOA | |
| SCHEMBL31488126 | 0.73 | MTNR1A (1.00) | KDM4EMTNR1AMTNR1BKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |