Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 10/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17223024 | 0.82 | RBP4 (0.50) | RBP4 | |
| SCHEMBL28146207 | 0.81 | RBP4 (0.48) | RBP4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28844203 | 0.79 | RBP4 (0.54) | RBP4SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28146205 | 0.79 | RBP4 (0.48) | RBP4SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27866038 | 0.78 | GRM2 (0.40) | HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL27885427 | 0.77 | TRPV1 (0.54) | RBP4 | |
| SCHEMBL17232802 | 0.77 | RBP4 (0.53) | RBP4SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28146200 | 0.76 | RBP4 (0.50) | RBP4 | |
| SCHEMBL27825724 | 0.75 | HSD11B1 (0.35) | KCNH2HCRTR2 | |
| SCHEMBL27948292 | 0.75 | SLC9A1 (0.48) | RBP4SLC9A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106794364-A | Substituted 4-phenylpiperidines, their preparation and use | 哥伦比亚大学董事会 | 2017-05-31 | — | — | CN | disclosed |