Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 10/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 9/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27948292 | 0.88 | SLC9A1 (0.48) | RBP4SLC9A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL17223034 | 0.81 | SMN1; SMN2 (0.52) | RBP4SLC9A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL27704480 | 0.81 | DRD2 (0.46) | RBP4KCNH2ADRA1D | |
| SCHEMBL28844354 | 0.81 | RBP4 (0.47) | RBP4SLC9A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL28147246 | 0.80 | RBP4 (0.49) | RBP4SLC9A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL28146207 | 0.79 | RBP4 (0.48) | RBP4CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL28844207 | 0.79 | RBP4 (0.48) | RBP4SLC9A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL28146200 | 0.79 | RBP4 (0.50) | RBP4 | |
| SCHEMBL27562125 | 0.79 | PARP10 (0.44) | KCNH2 | |
| SCHEMBL28146214 | 0.79 | SLC9A1 (0.56) | RBP4SLC9A1CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106794364-A | Substituted 4-phenylpiperidines, their preparation and use | 哥伦比亚大学董事会 | 2017-05-31 | — | — | CN | disclosed |