Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844401 | 0.85 | NPC1 (0.56) | RAB9ANPC1PKMMEN1GAA | |
| SCHEMBL28844391 | 0.82 | RAB9A (0.64) | RAB9ANPC1PKMMEN1GAA | |
| SCHEMBL5579208 | 0.76 | NPC1 (1.00) | RAB9ANPC1PKMMEN1GAA | |
| SCHEMBL29611011 | 0.76 | NPC1 (1.00) | RAB9ANPC1PKMMEN1GAA | |
| SCHEMBL16456324 | 0.72 | HPGD (0.74) | RAB9ANPC1PKMMEN1GAA | |
| SCHEMBL11942639 | 0.72 | ACHE (0.54) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL28409019 | 0.71 | PKM (0.47) | RAB9ANPC1PKMMEN1GAA | |
| SCHEMBL13232537 | 0.71 | MAPT (0.67) | RAB9ANPC1PKMMEN1GAA | |
| SCHEMBL31432954 | 0.71 | MAPT (0.67) | RAB9ANPC1PKMMEN1GAA | |
| SCHEMBL15448415 | 0.71 | HTT (0.50) | RAB9ANPC1PKMMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790752-B | Synthetic method of (iso) quinoline and quinoxaline substituted flavone and quinolone derivatives | 陕西师范大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-110790752-A | Synthesis method of (iso) quinoline and quinoxaline substituted flavone and quinolone derivatives | 陕西师范大学 | 2020-02-14 | — | — | CN | disclosed |