Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HAAO | P46952 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835976 | 0.84 | CYP1A2 (0.37) | KDM4EHSD17B10TSHRGAASMN1; SMN2 | |
| SCHEMBL8895803 | 0.83 | KDM4E (0.43) | KDM4EHSD17B10TSHRGAASMN1; SMN2 | |
| SCHEMBL16035544 | 0.83 | GABRA1 (0.43) | KDM4EHSD17B10TSHRGAASMN1; SMN2 | |
| SCHEMBL8816524 | 0.81 | SELL (0.41) | KDM4EHSD17B10ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL243841 | 0.81 | GAA (0.38) | KDM4EHSD17B10TSHRGAASMN1; SMN2 | |
| SCHEMBL27417962 | 0.80 | GABRP (0.41) | TSHRSMN1; SMN2HAAOALDH1A1CYP1A2 | |
| SCHEMBL28127936 | 0.79 | METAP2 (0.40) | TSHRHAAOCYP1A2GABRA1GABRB2 | |
| SCHEMBL18915 | 0.78 | GAA (0.38) | KDM4EHSD17B10TSHRGAASMN1; SMN2 | |
| SCHEMBL7369721 | 0.78 | MRGPRX4 (0.45) | KDM4EHSD17B10TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27287111 | 0.77 | GABRP (0.38) | KDM4EHSD17B10TSHRHAAOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732606-B | New cyclopentano [B] fluorenyl transition metal compound, the carbon monoxide-olefin polymeric comprising it and the method using its copolymer for preparing Alathon or ethene and alhpa olefin | 沙特基础工业爱思开NEXLENE私人有限公司 | 2017-06-09 | — | — | CN | disclosed |