Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152117 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAMAPTKMT2A | |
| SCHEMBL28153198 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAMAPTKMT2A | |
| SCHEMBL28153102 | 0.73 | LMNA (0.44) | ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL28845502 | 0.70 | KMT2A (0.30) | HPGDKMT2A | |
| SCHEMBL27426698 | 0.66 | CNR2 (0.39) | ALDH1A1HPGDCNR2 | |
| SCHEMBL14843311 | 0.63 | CNR2 (0.32) | CNR2 | |
| SCHEMBL6391156 | 0.63 | BACE1 (0.40) | ALDH1A1CNR2MAPTKMT2A | |
| SCHEMBL11764405 | 0.62 | NOTUM (0.48) | LMNAMAPTNPSR1 | |
| SCHEMBL19475042 | 0.61 | HPGD (0.41) | ALDH1A1HPGDLMNAMAPTFFAR4 | |
| SCHEMBL2941532 | 0.59 | MAPT (0.56) | ALDH1A1HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928127-A | Substituted piperidine class amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |