Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1569939 | 0.77 | FPR2 (0.40) | LMNAPIK3CAFPR2SCN9AALDH1A1 | |
| SCHEMBL28798403 | 0.77 | AKR1C3 (0.46) | LMNAPIK3CAFPR2SCN9AALDH1A1 | |
| SCHEMBL28152117 | 0.76 | ALDH1A1 (0.43) | LMNAPIK3CAALDH1A1HPGDMAPT | |
| SCHEMBL28153198 | 0.76 | ALDH1A1 (0.43) | LMNAPIK3CAALDH1A1HPGDMAPT | |
| SCHEMBL19280147 | 0.75 | PIK3CD (0.44) | PIK3CAFPR2SCN9AALDH1A1HTT | |
| SCHEMBL28845503 | 0.73 | ALDH1A1 (0.38) | LMNAALDH1A1HPGDMAPT | |
| SCHEMBL19280509 | 0.71 | PIK3CD (0.40) | PIK3CAFPR2SCN9AALDH1A1PIK3C3 | |
| SCHEMBL28153100 | 0.70 | LMNA (0.38) | LMNAPIK3C3SMN1; SMN2TSHRHTT | |
| SCHEMBL27634306 | 0.69 | FKBP1A (0.40) | LMNAPIK3CAFPR2SCN9AALDH1A1 | |
| SCHEMBL1317468 | 0.69 | CYP1A2 (0.55) | LMNAPIK3CAFPR2SCN9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928127-A | Substituted piperidine class amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |