SCHEMBL2884565

SCHEMBL2884565

O=C(Oc1c(Cl)ccc(Cl)c1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
F2 P00734 1/20 0.52
KMT2A Q03164 6/20 0.50
MAPT P10636 5/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 3/20 0.47
MEN1 O00255 3/20 0.47
PARP10 Q53GL7 1/20 0.47
ALDH1A1 P00352 2/20 0.44
PKM P14618 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A3 Q01959 1/20 0.44
GAA P10253 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
HTT P42858 1/20 0.44
TP53 P04637 1/20 0.44
JAK2 O60674 1/20 0.43
USP2 O75604 1/20 0.43
ESR1 P03372 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9161406 0.90 LMNA (0.50) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL5551848 0.84 LMNA (0.64) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL6939316 0.83 KMT2A (0.56) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL8209293 0.82 MAPT (0.47) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL10500445 0.82 KMT2A (0.46) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL9140586 0.81 CA12 (0.39) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL8205428 0.80 PKM (0.47) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL7919058 0.79 LMNA (0.47) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL29372731 0.78 LMNA (0.56) LMNAF2KMT2AMAPTSMN1; SMN2
SCHEMBL9139344 0.78 CA12 (0.40) LMNAF2KMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN claimed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN claimed
CN-113773423-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2021-12-10 CN claimed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US claimed
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN disclosed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN disclosed
CN-113773423-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2021-12-10 CN disclosed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US disclosed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US disclosed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US disclosed
EP-2373701-B1 ENHANCED PROCATALYST COMPOSITION AND PROCESS GRACE W R & CO (US) 2016-03-09 EP disclosed
EP-2373701-B1 ENHANCED PROCATALYST COMPOSITION AND PROCESS GRACE W R & CO (US) 2016-03-09 EP disclosed
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions W. R. GRACE & CO.-CONN. 2010-08-12 US disclosed
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions W. R. GRACE & CO.-CONN. 2010-08-12 US disclosed
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions W. R. GRACE & CO.-CONN. 2010-08-12 US disclosed
WO-2010078519-A1 PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO disclosed
US-20100173769-A1 Enhanced Procatalyst Composition and Process W. R. GRACE & CO.-CONN. 2010-07-08 US disclosed
US-20100173769-A1 Enhanced Procatalyst Composition and Process W. R. GRACE & CO.-CONN. 2010-07-08 US disclosed
US-20100173769-A1 Enhanced Procatalyst Composition and Process W. R. GRACE & CO.-CONN. 2010-07-08 US disclosed
WO-2010078503-A1 ENHANCED PROCATALYST COMPOSITION AND PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions PAH, DDC, DDT LMNA 4145/4885F2 653/4885KMT2A 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.