Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.44 |
| ▸ | MEN1 | O00255 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 14/20 | 0.43 |
| ▸ | CASP3 | P42574 | 4/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28155503 | 0.84 | RAB9A (0.43) | RAB9AMEN1KMT2ANPC1CASP3 | |
| SCHEMBL28154695 | 0.82 | RAB9A (0.46) | RAB9AMEN1KMT2ANPC1CASP3 | |
| SCHEMBL28154610 | 0.80 | NPC1 (0.49) | RAB9AMEN1KMT2ANPC1CASP3 | |
| SCHEMBL28845875 | 0.80 | NPC1 (0.52) | RAB9AMEN1KMT2ANPC1CASP3 | |
| SCHEMBL28002973 | 0.78 | RAB9A (0.54) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL16217116 | 0.78 | MEN1 (0.58) | RAB9AMEN1KMT2ANPC1CASP3 | |
| SCHEMBL28845877 | 0.76 | RAB9A (0.56) | RAB9AMEN1KMT2ANPC1TP53 | |
| SCHEMBL28154660 | 0.74 | NPC1 (0.70) | RAB9AMEN1KMT2ANPC1CASP3 | |
| SCHEMBL27986414 | 0.73 | PARP1 (0.56) | MEN1KMT2ASMN1; SMN2TDP1LMNA | |
| SCHEMBL27898729 | 0.73 | ALDH1A1 (0.41) | RAB9AMEN1KMT2ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254534-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2017-07-14 | — | — | CN | disclosed |