Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28846267 | 0.79 | CYP11B2 (0.40) | KDM4ETP53TDP1ESR1L3MBTL1 | |
| SCHEMBL29496277 | 0.75 | LMNA (0.52) | LMNAKDM4EGMNNTP53HSP90AA1 | |
| SCHEMBL22016210 | 0.75 | CCR1 (0.52) | TOP1LMNAKDM4EGMNNTP53 | |
| SCHEMBL28722018 | 0.75 | LMNA (0.52) | LMNAKDM4EGMNNTP53HSP90AA1 | |
| Phenanthroline SCHEMBL9275301 | 0.74 | LMNA (0.76) | TOP1LMNAKDM4EGMNNTP53 | |
| SCHEMBL28155587 | 0.74 | ESR1 (0.39) | LMNAKDM4ECYP2D6MAPTTSHR | |
| SCHEMBL2569765 | 0.73 | PSMD14 (0.55) | LMNAKDM4EGMNNTP53HSP90AA1 | |
| SCHEMBL29935933 | 0.73 | PSMD14 (0.55) | LMNAKDM4EGMNNTP53HSP90AA1 | |
| SCHEMBL22969602 | 0.73 | CCR1 (0.39) | LMNAKDM4EGMNNTP53HSP90AA1 | |
| SCHEMBL2653070 | 0.73 | CCR1 (0.39) | TOP1LMNAKDM4EGMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715425-A | Herbicidal quinolines | 先正达参股股份有限公司 | 2017-05-24 | — | — | CN | disclosed |