Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22025141 | 0.78 | MAPT (0.42) | ALDH1A1GAAMEN1KMT2ACYP2C9 | |
| SCHEMBL24575945 | 0.77 | CCR2 (0.43) | CCR2MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL10655616 | 0.77 | PLK1 (0.35) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL31222333 | 0.76 | PDE7A (0.46) | ALDH1A1KDM4EGLAGAAMEN1 | |
| SCHEMBL27049091 | 0.75 | CCR2 (0.36) | CCR2MAPT | |
| SCHEMBL25455606 | 0.75 | CCR2 (0.36) | ALDH1A1KDM4EGAACCR2MEN1 | |
| SCHEMBL3787206 | 0.75 | CCR2 (0.46) | ALDH1A1KDM4ECCR2MEN1KMT2A | |
| SCHEMBL3780224 | 0.75 | GAA (0.53) | ALDH1A1KDM4EGLAGAAMEN1 | |
| SCHEMBL5741501 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAGAAMEN1 | |
| Hydrochloric Acid SCHEMBL6712800 | 0.73 | ADRA2A (0.46) | ALDH1A1KDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572252-A | Isoindolinone inhibitors of MDM2-P53 interaction with anti-cancer activity | 阿斯泰克斯治疗有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-108290871-B | Isoindolinone inhibitors of MDM2-P53 interaction with anti-cancer activity | 阿斯泰克斯治疗有限公司 | 2022-08-23 | — | — | CN | disclosed |