Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689479 | 0.84 | ADRA2A (0.45) | MAPTPKMKMT2AMEN1HPGD | |
| SCHEMBL10655616 | 0.80 | PLK1 (0.35) | MAPTKMT2AMEN1HPGDLMNA | |
| SCHEMBL25455606 | 0.78 | CCR2 (0.36) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL27049091 | 0.78 | CCR2 (0.36) | MAPTPKM | |
| SCHEMBL28846956 | 0.78 | ALDH1A1 (0.46) | MAPTKMT2AMEN1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL6712800 | 0.77 | ADRA2A (0.46) | MAPTKMT2AMEN1LMNAALOX12 | |
| SCHEMBL31222335 | 0.77 | L3MBTL1 (0.44) | MAPTPKMKMT2AMEN1HPGD | |
| SCHEMBL12889181 | 0.75 | HPGD (0.45) | KMT2AMEN1HPGDTP53GAA | |
| SCHEMBL23016949 | 0.75 | MAPT (0.39) | MAPTPKMKMT2AMEN1HPGD | |
| SCHEMBL20112866 | 0.75 | MAPT (0.42) | MAPTPKMKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656781-A1 | A METHOD FOR THE SITE-SPECIFIC ENZYMATIC LABELLING OF NUCLEIC ACIDS IN VITRO BY INCORPORATION OF UNNATURAL NUCLEOTIDES | The Scripps Research Institute (US) | 2020-05-27 | — | — | EP | disclosed |