Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12263566 | 0.83 | GABRA1 (0.50) | HSP90AA1TLR9GABRA1GABRB1ALOX15 | |
| SCHEMBL10832047 | 0.81 | ALOX15 (0.41) | HSP90AA1TLR9GABRA1GABRB1ALOX15 | |
| SCHEMBL1539492 | 0.80 | HSP90AA1 (0.42) | HSP90AA1TLR9GABRA1GABRB1ALOX15 | |
| SCHEMBL16951419 | 0.79 | HSP90AA1 (0.38) | HSP90AA1TLR9GABRA1GABRB1ALOX15 | |
| SCHEMBL22425322 | 0.79 | GABRA1 (0.37) | GABRA1GABRB1ALOX15ALDH1A1MAPK1 | |
| SCHEMBL27777980 | 0.79 | LMNA (0.39) | HSP90AA1ALOX15ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11040026 | 0.79 | HSP90AA1 (0.38) | HSP90AA1TLR9GABRA1GABRB1ALOX15 | |
| SCHEMBL16561617 | 0.79 | GABRA1 (0.41) | HSP90AA1TLR9GABRA1GABRB1ALOX15 | |
| SCHEMBL10750208 | 0.79 | HSP90AA1 (0.38) | HSP90AA1TLR9GABRA1GABRB1ALOX15 | |
| SCHEMBL15464206 | 0.77 | APLNR (0.38) | GABRA1GABRB1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010530439-A | — | — | 2010-09-09 | — | — | JP | claimed |
| EP-2115059-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2009-11-11 | — | — | EP | claimed |
| WO-2008127753-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2008-10-23 | — | — | WO | claimed |
| US-20080221239-A1 | Flame retardant composition for use in styrenics | RECREATIONAL WATER PRODUCTS, INC. | 2008-09-11 | — | — | US | claimed |
| EP-0159915-A2 | Process for making ring-halogenated styrenes and their use | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1985-10-30 | — | — | EP | claimed |
| US-8513346-B2 | Flame retardant composition for use in styrenics | CHEMTURA CORPORATION (US) | 2013-08-20 | — | — | US | disclosed |
| CN-101652418-B | Flame retardant composition for use in styrenics | CHEMTURA CORP | 2012-12-19 | — | — | CN | disclosed |
| US-20120184638-A1 | Flame Retardant Composition for Use in Styrenics | LANXESS SOLUTIONS US INC. | 2012-07-19 | — | — | US | disclosed |
| CN-101652418-A | The fire-retardant combination that is used for styrene resin | CHEMTURA CORP US | 2010-02-17 | — | — | CN | disclosed |
| US-20080221239-A1 | Flame retardant composition for use in styrenics | RECREATIONAL WATER PRODUCTS, INC. | 2008-09-11 | — | — | US | disclosed |
| US-4686311-A | Dehydrohalogenation of haloethyl brominated benzenes | ETHYL CORPORATION (US) | 1987-08-11 | — | — | US | disclosed |
| US-4633026-A | DEHYDROHALOGENATION OF RING-HALOGENATED ALPHA- OR BETA-BROMOETHYL BENZENES WITH STRONG BASE, POLYOXYETHYLENE GLYCOL CATALYST, AMINE POLYMERIZATION INHIBITOR | ETHYL CORPORATION (US) | 1986-12-30 | — | — | US | disclosed |
| US-3867468-A | Production of dibromostyrene and alkyl bromide | YEDA RES & DEV | 1975-02-18 | — | — | US | disclosed |