Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030074 | 0.73 | OPRK1 (0.46) | OPRK1NPC1RAB9AKMT2APKM | |
| SCHEMBL12046104 | 0.69 | OPRK1 (0.39) | OPRK1NPC1RAB9AKMT2APKM | |
| SCHEMBL2524058 | 0.68 | OPRK1 (0.58) | OPRK1NPC1RAB9AKMT2APKM | |
| SCHEMBL30122813 | 0.68 | OPRK1 (0.45) | OPRK1NPC1RAB9AKMT2APKM | |
| SCHEMBL17968071 | 0.67 | MAPT (0.50) | OPRK1NPC1RAB9AKMT2APKM | |
| SCHEMBL14454718 | 0.66 | NOS3 (0.44) | NPC1RAB9AKMT2APKMLMNA | |
| SCHEMBL5388076 | 0.66 | OPRK1 (0.36) | OPRK1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7458656 | 0.66 | OPRK1 (0.37) | OPRK1NPC1RAB9AKMT2APKM | |
| SCHEMBL9636537 | 0.66 | OPRK1 (0.37) | OPRK1NPC1RAB9AKMT2APKM | |
| SCHEMBL28245328 | 0.64 | LMNA (0.50) | NPC1RAB9AKMT2ALMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104271552-B | Substituted heterocyclic acetamides as KAPPA Opioid Receptor (KOR) agonists | 雷迪博士实验室有限公司 | 2017-08-08 | — | — | CN | disclosed |