Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030074 | 0.71 | OPRK1 (0.46) | OPRK1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL29070050 | 0.68 | TRPA1 (0.44) | ALDH1A1COMTNPC1RAB9AMEN1 | |
| SCHEMBL334804 | 0.67 | TRPA1 (0.42) | ALDH1A1MEN1KMT2APOLBACHE | |
| SCHEMBL12046104 | 0.67 | OPRK1 (0.39) | OPRK1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL28847701 | 0.66 | OPRK1 (0.39) | OPRK1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL30122813 | 0.66 | OPRK1 (0.45) | OPRK1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL2524058 | 0.65 | OPRK1 (0.58) | OPRK1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL24828 | 0.64 | TRPA1 (0.54) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL17968071 | 0.64 | MAPT (0.50) | OPRK1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL7458656 | 0.63 | OPRK1 (0.37) | OPRK1ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235549-B2 | Benzamide, heteroarylamide and reverse amides | PFIZER INC. (US) | 2007-06-26 | — | — | US | claimed |