Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1950509 | 0.95 | BBOX1 (0.40) | BBOX1ACHEKDM4EMAPK1HIF1A | |
| Sulfuric Acid SCHEMBL1950510 | 0.94 | BBOX1 (0.39) | BBOX1ACHEKDM4EMAPK1HIF1A | |
| SCHEMBL18906117 | 0.92 | ACHE (0.42) | ACHEKDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL6118217 | 0.91 | POLB (0.36) | BBOX1ACHEKDM4EMAPK1HIF1A | |
| Iodide SCHEMBL23607565 | 0.90 | ACHE (0.41) | ACHEKDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL18331519 | 0.90 | KDM4E (0.43) | ACHEKDM4EMAPK1HIF1AMEN1 | |
| Hydrochloric Acid SCHEMBL3112798 | 0.90 | ACHE (0.41) | BBOX1ACHEKDM4EMAPK1HIF1A | |
| Bromide SCHEMBL23607571 | 0.90 | ACHE (0.41) | ACHEKDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL2952605 | 0.90 | KDM4E (0.43) | ACHEKDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL2944413 | 0.90 | KDM4E (0.43) | ACHEKDM4EMAPK1HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107257777-A | High solids pcc with cationic additive | OMYA国际股份公司 | 2017-10-17 | — | — | CN | claimed |
| CN-107257777-A | High solids pcc with cationic additive | OMYA国际股份公司 | 2017-10-17 | — | — | CN | disclosed |