Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28847857 | 0.95 | BBOX1 (0.39) | BBOX1ACHEENPP2KDM4EMAPK1 | |
| Sulfuric Acid SCHEMBL1950510 | 0.95 | BBOX1 (0.39) | BBOX1ACHEENPP2TGFBR1KDM4E | |
| SCHEMBL33607 | 0.91 | ACHE (0.43) | BBOX1ACHETGFBR1KDM4EMAPK1 | |
| SCHEMBL25422694 | 0.91 | ACHE (0.43) | BBOX1ACHETGFBR1KDM4EMAPK1 | |
| SCHEMBL153023 | 0.91 | POLB (0.37) | BBOX1ACHEENPP2 | |
| Sulfuric Acid SCHEMBL2774840 | 0.90 | ACHE (0.37) | BBOX1ACHEENPP2TGFBR1KDM4E | |
| Sulfuric Acid SCHEMBL6478255 | 0.90 | BBOX1 (0.34) | BBOX1ACHETGFBR1 | |
| Hydrochloric Acid SCHEMBL61004 | 0.90 | ACHE (0.42) | BBOX1ACHEENPP2KDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL21827668 | 0.90 | ACHE (0.42) | BBOX1ACHETGFBR1KDM4EMAPK1 | |
| Fluoride Ion SCHEMBL8578974 | 0.90 | ACHE (0.42) | BBOX1ACHETGFBR1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078109-B1 | USE OF AN AQUEOUS SUSPENSION AND/OR DISPERSION OF MINERAL MATERIALS CONTAINING A HYDROPHOBIC GROUP WATER-SOLUBLE COPOLYMER FOR MAKING A PAPER SHEET | COATEX SAS (FR) | 2013-04-10 | — | — | EP | claimed |
| US-8263819-B2 | Method for manufacturing a metallic hydroxide and oxide powder which is self-dispersing in water, powder and aqueous dispersion obtained, uses thereof | COATEX S.A.S. (FR) | 2012-09-11 | — | — | US | claimed |
| US-20120132843-A1 | USE OF COMPOSITE MATERIALS BASED ON CARBON NANOTUBES AS THICKENING AGENTS FOR AQUEOUS SOLUTIONS | C.N.R.S. (FR) | 2012-05-31 | — | — | US | claimed |
| US-20110160348-A1 | USE OF STRUCTURED WATER-SOLUBLE POLYMERS OBTAINED BY CONTROLLED RADICAL POLYMERIZATION AS A DISPERSANT AND AGENT FOR ASSISTING IN THE GRINDING OF MINERAL MATERIALS | COATEX S.A.S. (FR) | 2011-06-30 | — | — | US | claimed |
| US-20110135560-A1 | USE OF A WEAKLY IONIC ACRYLIC POLYMER IN THE SYNTHESIS OF PRECIPITATED CALCIUM CARBONATE | COATEX S.A.S. (FR) | 2011-06-09 | — | — | US | claimed |
| US-20100121127-A1 | METHOD FOR MANUFACTURING A METALLIC HYDROXIDE AND OXIDE POWDER WHICH IS SELF-DISPERSING IN WATER, POWDER AND AQUEOUS DISPERSION OBTAINED, USES THEREOF | COATEX S.A.S. (FR) | 2010-05-13 | — | — | US | claimed |
| US-20090308553-A1 | Method for Treating Mineral Materials Using Amphoteric Polymers, Mineral Materials Thereby Obtained, and their Usage as an Agent for Reducing the Quantity of Colloids in Manufacturing Paper | COATEX S.A.S. (FR) | 2009-12-17 | — | — | US | claimed |
| CN-113226376-A | Thermosensitive injectable gels based on macromolecular prodrugs as novel drug delivery platform | 内布拉斯加大学董事会 | 2021-08-06 | — | — | CN | disclosed |
| WO-2006086231-A9 | METHODS OF BLOCKING STAINS ON A SUBSTRATE TO BE PAINTED, AND COMPOSITES SUITABLE FOR USE IN SAID METHODS | EASTMAN CHEMICAL COMPANY (US) | 2014-11-27 | — | — | WO | disclosed |
| US-8263819-B2 | Method for manufacturing a metallic hydroxide and oxide powder which is self-dispersing in water, powder and aqueous dispersion obtained, uses thereof | COATEX S.A.S. (FR) | 2012-09-11 | — | — | US | disclosed |
| US-8221587-B2 | Use of an aqueous suspension and/or dispersion of mineral materials containing a hydrophobic group water-soluble copolymer for making a paper sheet | COATEX S.A.S. (FR) | 2012-07-17 | — | — | US | disclosed |
| US-7820752-B2 | Use of charged amphiphilic statistic polymers for thickening phase comprising giant micelles of surfactants and aqueous composition comprising same | RHODIA CHIMIE (FR) | 2010-10-26 | — | — | US | disclosed |
| US-20100121127-A1 | METHOD FOR MANUFACTURING A METALLIC HYDROXIDE AND OXIDE POWDER WHICH IS SELF-DISPERSING IN WATER, POWDER AND AQUEOUS DISPERSION OBTAINED, USES THEREOF | COATEX S.A.S. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20060177649-A1 | Methods of blocking stains on a substrate to be painted, and composites suitable for use in such methods | EASTMAN CHEMICAL COMPANY | 2006-08-10 | — | — | US | disclosed |
| EP-1664458-A2 | METHODS OF BLOCKING STAINS ON A SUBSTRATE TO BE PAINTED, AND COMPOSITES SUITABLE FOR USE IN SUCH METHODS | EASTMAN CHEMICAL COMPANY (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005075531-A1 | AMPHIPHILIC BLOCK AND GRAFT COPOLYMERS CONTAINING HEAVY ELEMENTS, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS X-RAY CONTRAST AGENTS | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2005-08-18 | — | — | WO | disclosed |
| US-20050119401-A1 | Use of charged amphiphilic statistic polymers for thickening phase comprising giant micelles of surfactants and aqueous composition comprising same | RHODIA CHIMIE (FR) | 2005-06-02 | — | — | US | disclosed |
| WO-2005030495-A2 | METHODS OF BLOCKING STAINS ON A SUBSTRATE TO BE PAINTED, AND COMPOSITES SUITABLE FOR USE IN SUCH METHODS | EASTMAN CHEMICAL COMPANY (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050069698-A1 | Methods of blocking stains on a substrate to be painted, and composites suitable for use in such methods | EASTMAN CHEMICAL COMPANY | 2005-03-31 | — | — | US | disclosed |
| US-20030209695-A1 | Dispersant composition | AKZO NOBEL N.V. (NL) | 2003-11-13 | — | — | US | disclosed |