Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21777097 | 0.98 | APEX1 (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL23607542 | 0.98 | APEX1 (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| SCHEMBL18906117 | 0.98 | ACHE (0.42) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| SCHEMBL10301522 | 0.96 | KDM4E (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| SCHEMBL18331519 | 0.96 | KDM4E (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| SCHEMBL2944413 | 0.96 | KDM4E (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| SCHEMBL2952605 | 0.96 | KDM4E (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| Bromide SCHEMBL23607571 | 0.96 | ACHE (0.41) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| Iodide SCHEMBL23607565 | 0.96 | ACHE (0.41) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| Bromide SCHEMBL23607539 | 0.95 | MEN1 (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119425650-A | Stationary phase for chromatography | 株式会社大赛璐 | 2025-02-14 | — | — | CN | disclosed |
| CN-112638519-B | stationary phase for chromatography | 株式会社大赛璐 | 2023-11-10 | — | — | CN | disclosed |
| CN-112638519-A | Stationary phase for chromatography | 株式会社大赛璐 | 2021-04-09 | — | — | CN | disclosed |
| EP-3287504-B1 | ADDITIVE COMPOSITION SUITABLE FOR VISCOSITY REDUCTION OF OIL-BASED DRILLING FLUID, OIL-BASED DRILLING FLUID AND USE THEREOF | UNIV CHINA PETROLEUM BEIJING (CN) | 2018-12-12 | — | — | EP | disclosed |
| EP-3287504-A1 | ADDITIVE COMPOSITION SUITABLE FOR VISCOSITY REDUCTION OF OIL-BASED DRILLING FLUID, OIL-BASED DRILLING FLUID AND USE THEREOF | China University of Petroleum (Beijing) (CN) | 2018-02-28 | — | — | EP | disclosed |
| US-9745501-B1 | Additive composition suitable for viscosity reduction of oil-based drilling fluid, oil-based drilling fluid and use thereof | CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) | 2017-08-29 | — | — | US | disclosed |
| EP-1781717-B1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL AG & CO KGAA (DE) | 2012-11-07 | — | — | EP | disclosed |
| US-20100249249-A1 | Reduction of the Formation of Biofilm by Means of Multifunctional Copolymers | HENKEL AG & CO. KGAA (DE) | 2010-09-30 | — | — | US | disclosed |
| EP-1781717-A1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006005358-A1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249249-A1 | Reduction of the Formation of Biofilm by Means of Multifunctional Copolymers | PGLS, FGB, MUC1 | ACHE 519/4885CHRM1 1161/4885CHRM3 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.